DnaJ (Hsp40) Homolog, Subfamily C, Member 12 (DNAJC12) protein (His tag)

Details for Product No. ABIN1098343, Supplier: Log in to see
Protein Name
  • DNAJC12
  • JDP1
  • Jdp1
  • mJDP1
  • DnaJ (Hsp40) homolog, subfamily C, member 12
  • DNAJC12
  • dnajc12
  • LOC100219658
  • Dnajc12
Origin
Human
6
1
1
1
Source
Escherichia coli (E. coli)
4
2
2
1
Protein Type
Recombinant
Purification tag / Conjugate
This DNAJC12 protein is labelled with His tag.
Application
SDS-PAGE (SDS)
Options
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Purification purified by chromatography
Purity > 90 % by SDS - PAGE
Background DNAJC12, also known as JDP1, is a member of the DnaJ/Hsp40 family. The members of the DnaJ/Hsp40 proteins are highly conserved through evolution, expressed in several tissues and act as co-chaperone regulating protein folding, transport, translational initiation and gene expression. DnaJC12 may play a role in protein folding and export and is thought to be involved in estrogen control and the development of breast cancer. This protein is expressed at high levels in brain, heart, and testis, and at reduced levels in kidney and stomach. Recombinant human DNAJC12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molecular Weight 26.0kDa (222aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
NCBI Accession NP_068572
Research Area Heat Shock Proteins
Comment

Synonyms: DnaJ (Hsp40) homolog, subfamily C, member 12, JDP1, RP11-57G10.2

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml (determined by Bradford assay)
Buffer 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 2 mM DTT, 100 mM NaCl
Storage 4 °C
Storage Comment Avoid repeated freezing and thawing cycles.
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 image for DnaJ (Hsp40) Homolog, Subfamily C, Member 12 (DNAJC12) protein (His tag) (ABIN1098343) DnaJ (Hsp40) Homolog, Subfamily C, Member 12 (DNAJC12) protein (His tag)
Background publications Mahlknecht, Voelter-Mahlknecht: "Chromosomal characterization and localization of the NAD+-dependent histone deacetylase gene sirtuin 1 in the mouse." in: International journal of molecular medicine, Vol. 23, Issue 2, pp. 245-52, 2009 (PubMed).

De Bessa, Salaorni, Patrão, Neto, Brentani, Nagai: "JDP1 (DNAJC12/Hsp40) expression in breast cancer and its association with estrogen receptor status." in: International journal of molecular medicine, Vol. 17, Issue 2, pp. 363-7, 2006 (PubMed).

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