CHMP5 Protein (His tag)
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- Target See all CHMP5 Proteins
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CHMP5 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product CHMP5 Protein
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- Comment
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Synonyms: Charged multivesicular body protein 5, C9orf83, CGI-34, HSPC177, PNAS-2, SNF7DC2, Vps60
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 30% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- Alternative Name
- CHMP5 (CHMP5 Products)
- Synonyms
- SNF7DC2 Protein, cgi-34 Protein, hspc177 Protein, pnas-2 Protein, vps60 Protein, chmp5 Protein, zgc:64125 Protein, C9orf83 Protein, HSPC177 Protein, PNAS-2 Protein, Vps60 Protein, 2210412K09Rik Protein, AW545668 Protein, RGD1305968 Protein, charged multivesicular body protein 5 S homeolog Protein, charged multivesicular body protein 5b Protein, charged multivesicular body protein 5 Protein, charged multivesicular body protein 5 L homeolog Protein, chromatin modifying protein 5 Protein, chmp5.S Protein, chmp5b Protein, CHMP5 Protein, chmp5.L Protein, chmp5 Protein, Chmp5 Protein
- Background
- CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression. Recombinant human CHMP5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 27 kDa (243aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_057494
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