SH3GLB1 Protein (His tag)
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- Target See all SH3GLB1 Proteins
- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SH3GLB1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
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- Comment
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Synonyms: Endophilin-B1, Bif-1, CGI-61, dJ612B15.2, PPP1R70
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
- Alternative Name
- SH3GLB1 (SH3GLB1 Products)
- Synonyms
- im:5777505 Protein, wu:fa08f03 Protein, wu:fb13e12 Protein, MGC79086 Protein, sh3glb1 Protein, wu:fc55h11 Protein, wu:fj98d09 Protein, AA409932 Protein, AI314629 Protein, AU015566 Protein, Bif-1 Protein, mKIAA0491 Protein, PPP1R70 Protein, dJ612B15.2 Protein, SH3-domain GRB2-like endophilin B1b Protein, SH3 domain GRB2 like, endophilin B1 S homeolog Protein, SH3 domain GRB2 like, endophilin B1 Protein, SH3 domain containing GRB2 like, endophilin B1 Protein, SH3-domain GRB2-like endophilin B1a Protein, SH3-domain GRB2-like B1 (endophilin) Protein, SH3 domain -containing GRB2-like endophilin B1 Protein, SH3 domain containing GRB2 like endophilin B1 Protein, sh3glb1b Protein, sh3glb1.S Protein, sh3glb1 Protein, SH3GLB1 Protein, sh3glb1a Protein, Sh3glb1 Protein
- Background
- SH3GLB1, also as known as endophilin-B1, belongs to the endophilin family. Endophilin B1 is a member of the B subgroup of the endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. This protein required for normal outer mitochondrial membrane dynamics. Also it required for coatomer-mediated retrograde transport in certain cells. SH3GLB1 has been shown to interact with SH3GLB2 and Bcl-2-associated X protein. This protein highly expressed in heart, skeletal muscle, kidney and placenta. Recombinant human SH3GLB1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 41.9kDa (373aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_057093
- Pathways
- Autophagy
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