CHMP1A Protein (His tag)
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- Target See all CHMP1A Proteins
- CHMP1A (Charged Multivesicular Body Protein 1A (CHMP1A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CHMP1A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CHMP1A Protein
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- Comment
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Synonyms: Charged multivesicular body protein 1a, CHMP1, PCOLN3, PRSM1, VPS46-1, VPS46A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol,1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- CHMP1A (Charged Multivesicular Body Protein 1A (CHMP1A))
- Alternative Name
- CHMP1A (CHMP1A Products)
- Synonyms
- CHMP1 Protein, PCH8 Protein, PCOLN3 Protein, PRSM1 Protein, VPS46-1 Protein, VPS46A Protein, 2900018H07Rik Protein, Pcoln3 Protein, charged multivesicular body protein 1A Protein, CHMP1A Protein, Chmp1a Protein
- Background
- Charged multivesicular body protein 1a, also known as CHMP1A, belongs to the vacuolar sorting protein family and functions as chromatin-modifying protein. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), as well as required for the formation of these bodies. The MVBs pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. CHMP1 interacts with VPS4B and localizes to early endosomes. Two isoforms, encoded by distinct genes, exists for CHMP1. They are designated CHMP1A and CHMP1B. Recombinant human CHMP1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 24.1 kDa (219aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_002759
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