TNRC5 Protein (His tag)
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- Target See all TNRC5 (CNPY3) Proteins
- TNRC5 (CNPY3) (Canopy 3 Homolog (CNPY3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TNRC5 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CNPY3 Protein
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- Comment
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Synonyms: Canopy 3 homolog, CAG4A, ERDA5, PRAT4A, TNRC5
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- TNRC5 (CNPY3) (Canopy 3 Homolog (CNPY3))
- Alternative Name
- CNPY3 (CNPY3 Products)
- Synonyms
- TNRC5 Protein, cnpy3 Protein, 1600025D17Rik Protein, 2410050O22Rik Protein, AI413153 Protein, CAG4A Protein, ERDA5 Protein, PRAT4A Protein, Tnrc5 Protein, im:6892510 Protein, canopy FGF signaling regulator 3 Protein, canopy FGF signaling regulator 3 L homeolog Protein, trinucleotide repeat containing 5 Protein, CNPY3 Protein, cnpy3 Protein, Cnpy3 Protein, cnpy3.L Protein, tnrc5 Protein
- Background
- Canopy 3 homolog, also known as CNPY3, is Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. This protein is required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, CNPY3i s required for both innate and adaptive immune responses. Recombinant human CNPY3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 29.9 kDa (271aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_006577
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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