HOPX Protein (His tag)
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- Target See all HOPX Proteins
- HOPX (HOP Homeobox (HOPX))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HOPX protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HOPX Protein
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- Comment
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Synonyms: Homeodomain-only protein, CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- HOPX (HOP Homeobox (HOPX))
- Alternative Name
- HOPX (HOPX Products)
- Synonyms
- CAMEO Protein, HOD Protein, HOP Protein, LAGY Protein, NECC1 Protein, OB1 Protein, SMAP31 Protein, TOTO Protein, 1110018K11Rik Protein, 1200015P04Rik Protein, 2300002F06Rik Protein, AI848177 Protein, AW490897 Protein, Cameo Protein, Hdop Protein, Hod Protein, Hop Protein, Ob1 Protein, Obl Protein, Toto Protein, GIIg15b Protein, HOPX Protein, hod Protein, hop Protein, ob1 Protein, lagy Protein, toto Protein, cameo Protein, necc1 Protein, smap31 Protein, MGC147344 Protein, HOP homeobox Protein, HOPX Protein, Hopx Protein, hopx Protein
- Background
- HOPX, also known as homeodomain-only protein, acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. This protein prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Recombinant human HOPX protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Molecular Weight
- 10.8 kDa (97aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_631957
- Pathways
- Regulation of Muscle Cell Differentiation
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