HAND1 Protein (His tag)
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- Target See all HAND1 Proteins
- HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HAND1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HAND1 Protein
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- Comment
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Synonyms: Heart and neural crest derivatives-expressed protein 1, bHLHa27, eHand, Hxt, Thing1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))
- Alternative Name
- HAND1 (HAND1 Products)
- Synonyms
- CATG Protein, CG Protein, Hxt Protein, Thing1 Protein, bHLHa27 Protein, eHand Protein, eHAND Protein, hand-1 Protein, hand1-A Protein, HXT Protein, HAND1 Protein, hxt Protein, thing1 Protein, EHAND Protein, Hand1 Protein, Ehand1 Protein, Th1 Protein, cathepsin G Protein, heart and neural crest derivatives expressed 1 Protein, heart and neural crest derivatives expressed 1 L homeolog Protein, CTSG Protein, HAND1 Protein, Hand1 Protein, hand1.L Protein, hand1 Protein
- Background
- HAND1 belongs to the basic helix-loop-helix family of transcription factors. This protein is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. Recombinant human HAND1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 26 kDa (238aa)
- NCBI Accession
- NP_004812
- Pathways
- Tube Formation
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