HAND1 Protein (His tag)

Catalog No. ABIN1098692

Product Details

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HAND1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purity: > 90 % by SDS - PAGE

Application Details

Comment:

Synonyms: Heart and neural crest derivatives-expressed protein 1, bHLHa27, eHand, Hxt, Thing1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Alternative Name: HAND1 (HAND1 Products)

Synonyms: CATG Protein, CG Protein, Hxt Protein, Thing1 Protein, bHLHa27 Protein, eHand Protein, eHAND Protein, hand-1 Protein, hand1-A Protein, HXT Protein, HAND1 Protein, hxt Protein, thing1 Protein, EHAND Protein, Hand1 Protein, Ehand1 Protein, Th1 Protein, cathepsin G Protein, heart and neural crest derivatives expressed 1 Protein, heart and neural crest derivatives expressed 1 L homeolog Protein, CTSG Protein, HAND1 Protein, Hand1 Protein, hand1.L Protein, hand1 Protein

Background: HAND1 belongs to the basic helix-loop-helix family of transcription factors. This protein is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. Recombinant human HAND1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 26 kDa (238aa)

NCBI Accession: NP_004812

Pathways: Tube Formation