CD2 Protein (CD2) (His tag)
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- Target See all CD2 Proteins
- CD2
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CD2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CD2 Protein
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- Comment
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Synonyms: T-cell surface antigen CD2, SRBC, T11
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4 M Urea
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- CD2
- Alternative Name
- CD2 (CD2 Products)
- Synonyms
- CD2 Protein, LFA-2 Protein, Ly-37 Protein, Ly37 Protein, SRBC Protein, T11 Protein, CD2R Protein, LFA2 Protein, OX-34 Protein, OX34 Protein, CD2 molecule Protein, CD2 antigen Protein, Cd2 molecule Protein, CD2 Protein, Cd2 Protein
- Background
- CD2, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms. Recombinant human CD2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 23.8 kDa (209aa)
- NCBI Accession
- NP_001758
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