YARS Protein (AA 2-528, full length) (GST tag)

Catalog No. ABIN7479162

Product Details

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Protein Type: Recombinant

Protein Characteristics: AA 2-528, full length

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This YARS protein is labelled with GST tag.

Application: ELISA

Sequence: GDAPSPEEKL HLITRNLQEV LGEEKLKEIL KERELKIYWG TATTGKPHVA YFVPMSKIAD FLKAGCEVTI LFADLHAYLD NMKAPWELLE LRVSYYENVI KAMLESIGVP LEKLKFIKGT DYQLSKEYTL DVYRLSSVVT QHDSKKAGAE VVKQVEHPLL SGLLYPGLQA LDEEYLKVDA QFGGIDQRKI FTFAEKYLPA LGYSKRVHLM NPMVPGLTGS KMSSSEEESK IDLLDRKEDV KKKLKKAFCE PGNVENNGVL SFIKHVLFPL KSEFVILRDE KWGGNKTYTA YVDLEKDFAA EVVHPGDLKN SVEVALNKLL DPIREKFNTP ALKKLASAAY PDPSKQKPMA KGPAKNSEPE EVIPSRLDIR VGKIITVEKH PDADSLYVEK IDVGEAEPRT VVSGLVQFVP KEELQDRLVV VLCNLKPQKM RGVESQGMLL CASIEGINRQ VEPLDPPAGS APGEHVFVKG YEKGQPDEEL KPKKKVFEKL QADFKISEEC IAQWKQTNFM TKLGSISCKS LKGGNIS

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: 95 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Target Details

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Alternative Name: Tyrosyl-tRNA synthetase, cytoplasmic protein (Yars Products)

Synonyms: CMTDIC Protein, TYRRS Protein, YRS Protein, YTS Protein, AL024047 Protein, AU018965 Protein, cb204 Protein, wu:fk52b08 Protein, YARS Protein, cmtdic Protein, tyrrs Protein, yrs Protein, yts Protein, CG4561 Protein, Dmel\\CG4561 Protein, TyrRS Protein, anon-EST:Posey261 Protein, dYARS Protein, GB10789 Protein, tyrosyl-tRNA synthetase Protein, tyrosyl-tRNA synthetase L homeolog Protein, tyrosyl-tRNA synthetase, putative Protein, tyrosine--tRNA ligase Protein, Tyrosyl-tRNA synthetase Protein, tyrosine--tRNA ligase, cytoplasmic Protein, YARS Protein, Yars Protein, yars Protein, yars.L Protein, MAL8P1.125 Protein, MEFER_RS04475 Protein, TyrRS Protein, LOC413909 Protein, LOC100163888 Protein, LOC100282315 Protein

Background: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) Defects in YARS are the cause of Charcot-Marie-Tooth disease dominant intermediate type C (CMTDIC) [MIM:608323]. CMTDIC is a form of Charcot-Marie-Tooth disease characterized by clinical and pathologic features intermediate between demyelinating and axonal peripheral neuropathies, and motor median nerve conduction velocities ranging from 25 to 45 m/sec

Molecular Weight: 86.4 kD

UniProt: P54577