GM2A Protein (AA 32-193, full length) (GST tag)

Catalog No. ABIN7479205

Product Details

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Protein Type: Recombinant

Protein Characteristics: AA 32-193, full length

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GM2A protein is labelled with GST tag.

Application: ELISA

Sequence: SSFSWDNCDE GKDPAVIRSL TLEPDPIIVP GNVTLSVMGS TSVPLSSPLK VDLVLEKEVA GLWIKIPCTD YIGSCTFEHF CDVLDMLIPT GEPCPEPLRT YGLPCHCPFK EGTYSLPKSE FVVPDLELPS WLTTGNYRIE SVLSSSGKRL GCIKIAASLK GI

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: 95 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Target Details

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Alternative Name: Ganglioside GM2 activator protein (GM2A Products)

Synonyms: GM2A Protein, fb96e04 Protein, fb96e10 Protein, wu:fb96e04 Protein, wu:fb96e10 Protein, zgc:110188 Protein, MGC84154 Protein, GM2-AP Protein, SAP-3 Protein, AA408702 Protein, AW215435 Protein, GM2 ganglioside activator Protein, GM2 ganglioside activator L homeolog Protein, GM2 ganglioside activator protein Protein, Gm2a Protein, GM2A Protein, gm2a Protein, gm2a.L Protein

Background: Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3

Molecular Weight: 45 kD

UniProt: P17900