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GM2A Products

(GM2 Ganglioside Activator (GM2A))

Categories

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009].

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Featured GM2A Categories

GM2A Antibodies

High quality antibodies with extensive validation data.

GM2A ELISA Kits

Reliable ELISA kits for a wide range of species.

GM2A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GM2A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (4)
Cat. No. ABIN7153574
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN652023
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN768674
Quantity 50 μg
Datasheet Datasheet

Recommended GM2A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956281
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974789
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN512506
Quantity 96 tests
Datasheet Datasheet

Recommended GM2A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123178
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355279
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355281
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GM2A products

Potprommanee, Ma, Shank, Juan, Liao, Chen, Yu: "GM2-activator protein: a new biomarker for lung cancer." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 10, Issue 1, pp. 102-9, (2015) (PubMed).

Xu, Fang, Zhu, Dai, Nie, Chen, Qin, Wang, Wang, Qiao: "Cigarette smoking exposure alters pebp1 DNA methylation and protein profile involved in MAPK signaling pathway in mice testis." in: Biology of reproduction, Vol. 89, Issue 6, pp. 142, (2013) (PubMed).

Todeschini, Dos Santos, Handa, Hakomori: "Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8123-33, (2007) (PubMed).

Synonyms and alternative names related to GM2A

GM2 ganglioside activator (Gm2a), GM2 ganglioside activator (GM2A), GM2 ganglioside activator (gm2a), GM2 ganglioside activator L homeolog (gm2a.L), GM2 ganglioside activator protein (Gm2a), AA408702, AW215435, fb96e04, fb96e10, GM2-AP, GM2A, MGC84154, SAP-3, wu:fb96e04, wu:fb96e10, zgc:110188

Protein level used designations for GM2A

  • GM2 ganglioside activator protein
  • ganglioside GM2 activator
  • GM2 ganglioside activator
  • GM2 activator protein
  • cerebroside sulfate activator protein
  • shingolipid activator protein 3
  • sphingolipid activator protein 3
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