NR1I2 Protein (AA 1-434) (His tag)

Catalog No. ABIN1642709

Product Details

Target: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Protein Type: Recombinant

Protein Characteristics: AA 1-434

Origin: Rhesus Monkey

Source: Yeast

Purification tag / Conjugate: This NR1I2 protein is labelled with His tag.

Application: ELISA

Sequence: MEVRPKEGWN HADFVYCEDT EFAPGKPTVN ADEEVGGPQI CRVCGDKATG YHFNVMTCEG CKGFFRRAMK RNARLRCPFR KGACEITRKT RRQCQACRLR KCLESGMKKE MIMSDAAVEE RRALIKRKKR ERIGTQPPGV QGLTEEQRMM IRELMDAQMK TFDTTFSHFK NFRLPGVLSS GCEMPESLQA PSREEAAKWN QVRKDLWSVK VSVQLRGEDG SVWNYKPPAD NGGKEIFSLL PHMADMSTYM FKGIINFAKV ISYFRDLPIE DQISLLKGAT FELCQLRFNT VFNAETGTWE CGRLSYCLED PAGGFQQLLL EPMLKFHYML KKLQLHEEEY VLMQAISLFS PDRPGVVQHR VVDQLQEQYA ITLKSYIECN RPQPAHRFLF LKIMAMLTEL RSINAQHTQR LLRIQDIHPF ATPLMQELFG ITGS

Specificity: Macaca mulatta (Rhesus macaque)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Alternative Name: Nuclear receptor subfamily 1 group I member 2 (NR1I2) (NR1I2 Products)

Synonyms: BXR Protein, ONR1 Protein, PAR Protein, PAR1 Protein, PAR2 Protein, PARq Protein, PRR Protein, PXR Protein, SAR Protein, SXR Protein, PXR.1 Protein, PXR.2 Protein, PXR1 Protein, mPXR Protein, bxr Protein, nr1i2 Protein, onr1 Protein, xonr1 Protein, nuclear receptor subfamily 1 group I member 2 Protein, nuclear receptor subfamily 1, group I, member 2 Protein, nuclear receptor subfamily 1 group I member 2 S homeolog Protein, NR1I2 Protein, Nr1i2 Protein, nr1i2.S Protein, nr1i2 Protein

Background: Recommended name: Nuclear receptor subfamily 1 group I member 2.
Alternative name(s): Orphan nuclear receptor PXR Pregnane X receptor

UniProt: Q8SQ01

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway