CD72 Protein (AA 117-226) (His tag,TRX tag)
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- Target See all CD72 Proteins
- CD72 (CD72 Molecule (CD72))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 117-226
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CD72 protein is labelled with His tag,TRX tag.
- Purpose
- Recombinant Human B-Cell Differentiation Antigen CD72/Lyb-2 (N-Trx, 6His)
- Sequence
- MSDKIIHLTD DSFDTDVLKA DGAILVDFWA EWCGPCKMIA PILDEIADEY QGKLTVAKLN IDQNPGTAPK YGIRGIPTLL LFKNGEVAAT KVGALSKGQL KEFLDANLAG SGSGHMHHHH HHSSGLVPRG SGMKETAAAK FERQHMDSPD LGTDDDDKAM ADIGSMRYLQ VSQQLQQTNR VLEVTNSSLR QQLRLKITQL GQSAEDLQGS RRELAQSQEA LQVEQRAHQA AEGQLQACQA DRQKTKETLQ SEEQQRRALE QKLSNMENRL KPFFTC
- Characteristics
- Recombinant Human B-Cell Differentiation Antigen CD72/CD72 is produced with our E. coli expression system. The target protein is expressed with sequence (Arg117-Cys226) of Human CD72.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CD72 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- CD72 (CD72 Molecule (CD72))
- Alternative Name
- CD72 (CD72 Products)
- Synonyms
- CD72c Protein, Ly-19 Protein, Ly-32 Protein, Ly-m19 Protein, Lyb-2 Protein, CD72b Protein, LYB2 Protein, CD72 antigen Protein, CD72 molecule Protein, Cd72 Protein, CD72 Protein
- Background
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B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.
Alternative Names: B-Cell Differentiation Antigen CD72, Lyb-2, CD72 - Molecular Weight
- 30.6 kDa
- UniProt
- P21854
- Pathways
- BCR Signaling
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