ASB13 Protein (AA 1-278) (His tag)

Catalog No. ABIN1692421

Product Details

Target: ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))

Protein Type: Recombinant

Protein Characteristics: AA 1-278

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ASB13 protein is labelled with His tag.

Purpose: Recombinant Human Ankyrin Repeat and SOCS Box Protein 13/ASB13 (N-6His)

Sequence: MNHKVHHHHH HMEPRAADGC FLGDVGFWVE RTPVHEAAQR GESLQLQQLI ESGACVNQVT VDSITPLHAA SLQGQARCVQ LLLAAGAQVD ARNIDGSTPL CDACASGSIE CVKLLLSYGA KVNPPLYTAS PLHEACMSGS SECVRLLIDV GANLEAHDCH FGTPLHVACA REHLDCVKVL LNAGANVNAA KLHETALHHA AKVKNVDLIE MLIEFGGNIY ARDNRGKKPS DYTWSSSAPA KCFEYYEKTP LTLSQLCRVN LRKATGVRGL EKIAKLNIPP RLIDYLSYN

Characteristics: Recombinant Human Ankyrin repeat and SOCS box protein 13/ASB13 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asn278) of Human ASB13 fused with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 4M Urea.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))

Alternative Name: ASB13 (ASB13 Products)

Synonyms: 2210015B19Rik Protein, 6430573K02Rik Protein, Asb-13 Protein, C85285 Protein, ankyrin repeat and SOCS box-containing 13 Protein, ankyrin repeat and SOCS box containing 13 Protein, Asb13 Protein, ASB13 Protein

Sub Type: Fusionprotein

Background: Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alternative Names: Ankyrin repeat and SOCS box protein 13, ASB13,

Molecular Weight: 31.4 kDa

UniProt: Q8WXK3