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ASB13 Protein (His tag)

ASB13 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318157
  • Target See all ASB13 Proteins
    ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This ASB13 protein is labelled with His tag.
    Purpose
    Recombinant Human ASB13 Protein (His Tag)
    Sequence
    Met 1-Asn278
    Characteristics
    Recombinant Human Ankyrin repeat and SOCS box protein 13 is produced by our E.coli expression system and the target gene encoding Met1-Asn278 is expressed with a 6His tag at the N-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ASB13 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 4M Urea.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))
    Alternative Name
    ASB13 (ASB13 Products)
    Synonyms
    2210015B19Rik Protein, 6430573K02Rik Protein, Asb-13 Protein, C85285 Protein, ankyrin repeat and SOCS box-containing 13 Protein, ankyrin repeat and SOCS box containing 13 Protein, Asb13 Protein, ASB13 Protein
    Background

    Background: Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

    Synonym: Ankyrin repeat and SOCS box protein 13, ASB13,

    Molecular Weight
    31.4 kDa
    UniProt
    Q8WXK3
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