ASB13 Protein (His tag)
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- Target See all ASB13 Proteins
- ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ASB13 protein is labelled with His tag.
- Purpose
- Recombinant Human ASB13 Protein (His Tag)
- Sequence
- Met 1-Asn278
- Characteristics
- Recombinant Human Ankyrin repeat and SOCS box protein 13 is produced by our E.coli expression system and the target gene encoding Met1-Asn278 is expressed with a 6His tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ASB13 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 4M Urea.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))
- Alternative Name
- ASB13 (ASB13 Products)
- Synonyms
- 2210015B19Rik Protein, 6430573K02Rik Protein, Asb-13 Protein, C85285 Protein, ankyrin repeat and SOCS box-containing 13 Protein, ankyrin repeat and SOCS box containing 13 Protein, Asb13 Protein, ASB13 Protein
- Background
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Background: Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Synonym: Ankyrin repeat and SOCS box protein 13, ASB13,
- Molecular Weight
- 31.4 kDa
- UniProt
- Q8WXK3
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