FKBP2 Protein (AA 22-142) (His tag)

Catalog No. ABIN1880661

Product Details

Target: FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Protein Type: Recombinant

Protein Characteristics: AA 22-142

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This FKBP2 protein is labelled with His tag.

Purpose: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP2/FKBP22/FKBP13 (C-6His)

Sequence: ATGAEGKRKL QIGVKKRVDH CPIKSRKGDV LHMHYTGKLE DGTEFDSSLP QNQPFVFSLG TGQVIKGWDQ GLLGMCEGEK RKLVIPSELG YGERGAPPKI PGGATLVFEV ELLKIERRTE LVDHHHHHH

Characteristics: Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP2/FKBP2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala22-Leu142) of Human FKBP2 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150mm NaCl, pH 7.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Alternative Name: FKBP2 (FKBP2 Products)

Synonyms: FKBP-13 Protein, PPIase Protein, FKBP12 Protein, Fkbp2 Protein, 13kDa Protein, FKBP-2 Protein, mFKBP13 Protein, mFKBP2 Protein, RGD1560660 Protein, zgc:101826 Protein, FK506 binding protein 2 Protein, FK506 binding protein 1a Protein, FK506 binding protein 2 L homeolog Protein, FKBP2 Protein, Fkbp1a Protein, Fkbp2 Protein, fkbp2 Protein, fkbp2.L Protein

Sub Type: Fusionprotein

Background: Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds.
Alternative Names: Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein.

Molecular Weight: 14.3 kDa

UniProt: P26885