ENPP2 Protein (AA 49-863) (His tag)
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- Target See all ENPP2 Proteins
- ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 49-863
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ENPP2 protein is labelled with His tag.
- Sequence
- AA 49-863
- Characteristics
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 94.5 kDa. The protein migrates as 120-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ENPP2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.
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- Target
- ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
- Alternative Name
- ENPP-2 (ENPP2 Products)
- Synonyms
- ATX Protein, ATX-X Protein, AUTOTAXIN Protein, LysoPLD Protein, NPP2 Protein, PD-IALPHA Protein, PDNP2 Protein, Npps2 Protein, PD-Ialpha Protein, Pdnp2 Protein, MGC132047 Protein, atx Protein, zgc:63550 Protein, autotaxin Protein, enpp2 Protein, enpp2a Protein, enpp2b Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog Protein, ENPP2 Protein, Enpp2 Protein, enpp2 Protein, enpp2.L Protein, enpp2.S Protein
- Background
- Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP2 contains two SMB (somatomedin-B) domains. ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.
- Molecular Weight
- 94.5 kDa
- NCBI Accession
- NP_001035181
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