FSTL1 Protein (AA 21-308) (His tag)

Catalog No. ABIN2181121

Product Details

Target: FSTL1 (Follistatin-Like 1 (FSTL1))

Protein Type: Recombinant

Protein Characteristics: AA 21-308

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FSTL1 protein is labelled with His tag.

Sequence: AA 21-308

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.7 kDa. The protein migrates as 35-50 kDa under reducing (R) condition (SDS-PAGE) due to differtent glycosylation.

Purity: >95 % as determined by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

References

Dong, Geng, Li, Li, Yan, Fang, Li, Dong, Liu, Li, Yang, Zheng, Xie, Liang, Dai, Liu, Yin, Noble, Jiang, Ning: "Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice." in: The Journal of experimental medicine, Vol. 212, Issue 2, pp. 235-52, (2015) (PubMed).

Target Details

Target: FSTL1 (Follistatin-Like 1 (FSTL1))

Alternative Name: Follistatin-Like 1 (FSTL1 Products)

Synonyms: FRP Protein, FSL1 Protein, MIR198 Protein, AI316791 Protein, AW107808 Protein, Fstl Protein, TSC-36 Protein, Frp Protein, fstl1 Protein, wu:fc75h02 Protein, zgc:110703 Protein, FLIK Protein, FSTL1 Protein, DKFZp469P101 Protein, follistatin like 1 Protein, follistatin-like 1 Protein, follistatin-like 1a Protein, Follistatin-related protein 1 Protein, follistatin-related protein 1 Protein, follistatin like 1 L homeolog Protein, FSTL1 Protein, Fstl1 Protein, fstl1a Protein, fstl1 Protein, LOC101909195 Protein, fstl1.L Protein

Background: Follistatin-related protein 1 (FSTL1) is also known as Follistatin-like protein 1 (FRP). FSTL1 is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain and one VWFC domain. FSTL1 is overexpressed in synovial tissues from rheumatoid arthritis. Follistatin-like protein 1 / FSTL1 may modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 binds heparin.

Molecular Weight: 33.8 kDa