S100A14 Protein (AA 1-104) (His tag)
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- Target See all S100A14 Proteins
- S100A14 (S100 Calcium Binding Protein A14 (S100A14))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-104
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This S100A14 protein is labelled with His tag.
- Sequence
- AA 1-104
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.5 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE).
- Purity
- >92 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product S100A14 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 8.0
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- S100A14 (S100 Calcium Binding Protein A14 (S100A14))
- Alternative Name
- S100A14 (S100A14 Products)
- Synonyms
- BCMP84 Protein, S100A15 Protein, 1110013O05Rik Protein, S100a15 Protein, S114 Protein, S100A14 Protein, S100 calcium binding protein A14 Protein, S100A14 Protein, S100a14 Protein
- Background
- Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114),which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.
- Molecular Weight
- 12.5 kDa
- Pathways
- Activation of Innate immune Response, S100 Proteins
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