VSIG4 Protein (AA 20-283) (His tag)
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- Target See all VSIG4 Proteins
- VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-283
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VSIG4 protein is labelled with His tag.
- Sequence
- AA 20-283
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30 kDa. The protein migrates as 45-48 kDa under reducing (R) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product VSIG4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
- Alternative Name
- VSIG4 (VSIG4 Products)
- Synonyms
- DKFZp468O0322 Protein, CRIg Protein, Z39IG Protein, A530061A11 Protein, BC025105 Protein, V-set and immunoglobulin domain containing 4 Protein, VSIG4 Protein, Vsig4 Protein
- Background
- V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.
- Molecular Weight
- 30.1 kDa
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