BRDT Protein (AA 21-137) (His tag,DYKDDDDK Tag)
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- Target See all BRDT Proteins
- BRDT (Bromodomain, Testis-Specific (BRDT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-137
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BRDT protein is labelled with His tag,DYKDDDDK Tag.
- Application
- Binding Studies (Bind), Screening Assay (ScA)
- Characteristics
- The peptide corresponding to amino acids 21-137 that contains the bromodomain sequences of BRDT (accession number NP_001717.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20 kDa. It shows binding specificity for acetylated H2BK12/15, H3K9/14/18/23, H4K12, H4K5/8, H4K8/12, H4K12/16, H4K5/12, H4K5/8/12/16 and H4K5/8/12/16.
- Top Product
- Discover our top product BRDT Protein
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- Application Notes
- Recombinant BRDT (21-137) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
- Restrictions
- For Research Use only
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- Handling Advice
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Storage
- -80 °C
- Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- Target
- BRDT (Bromodomain, Testis-Specific (BRDT))
- Alternative Name
- BRDT (BRDT Products)
- Synonyms
- BRD6 Protein, CT9 Protein, 7420412D09Rik Protein, Brd6 Protein, Fsrg3 Protein, BRDT Protein, MGC151933 Protein, fi25h02 Protein, si:dkeyp-85h7.3 Protein, wu:fi25h02 Protein, bromodomain testis associated Protein, bromodomain, testis-specific Protein, bromodomain, testis-specific L homeolog Protein, BRDT Protein, Brdt Protein, brdt.L Protein, brdt Protein
- Background
- BRDT is similar to the RING3 protein family. It possesses two bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain functions as a 'reader' of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets.
- Molecular Weight
- 20 kDa
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