DAB1 Protein (Myc-DYKDDDDK Tag)
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- Target See all DAB1 Proteins
- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DAB1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human DAB1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DAB1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
- Alternative Name
- Dab1 (DAB1 Products)
- Synonyms
- AI956902 Protein, C630028C02Rik Protein, scm Protein, scr Protein, scrambler Protein, yot Protein, disabled-1 Protein, LOC100232823 Protein, si:dkey-242m13.1 Protein, DAB1 Protein, zgc:136547 Protein, DAB1, reelin adaptor protein Protein, disabled 1 Protein, disabled homolog 1 Protein, Dab, reelin signal transducer, homolog 1a (Drosophila) Protein, Dab, reelin signal transducer, homolog 1b (Drosophila) Protein, DAB1 Protein, Dab1 Protein, LOC100232823 Protein, dab1a Protein, dab1b Protein
- Background
- The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
- Molecular Weight
- 59.8 kDa
- NCBI Accession
- NP_066566
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