CTPS2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all CTPS2 Proteins
- CTPS2 (CTP Synthase II (CTPS2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CTPS2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CTP synthase 2 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CTPS2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CTPS2 (CTP Synthase II (CTPS2))
- Alternative Name
- Ctp Synthase 2 (CTPS2 Products)
- Synonyms
- A830031M15Rik Protein, AI326475 Protein, Ctpsh Protein, CTP synthase 2 L homeolog Protein, CTP synthase 2 Protein, cytidine 5'-triphosphate synthase 2 Protein, ctps2.L Protein, CTPS2 Protein, ctps2 Protein, Ctps2 Protein
- Background
- The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 65.5 kDa
- NCBI Accession
- NP_001137474
- Pathways
- Ribonucleoside Biosynthetic Process
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