CABLES1 Protein (His tag)
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- Target See all CABLES1 Proteins
- CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CABLES1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CABLES1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CABLES1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
- Alternative Name
- Cables1 (CABLES1 Products)
- Synonyms
- CABLES1 Protein, si:dkey-2p18.3 Protein, CABL1 Protein, CABLES Protein, HsT2563 Protein, IK3-1 Protein, Cables Protein, ik3-1 Protein, Cdk5 and Abl enzyme substrate 1 Protein, CDK5 and Abl enzyme substrate 1 Protein, CABLES1 Protein, cables1 Protein, CpipJ_CPIJ019832 Protein, Cables1 Protein
- Background
- This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 41.7 kDa
- NCBI Accession
- NP_612384
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