CBY1/PGEA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
-
- Target See all CBY1/PGEA1 (CBY1) Proteins
- CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CBY1/PGEA1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human CBY1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CBY1 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))
- Alternative Name
- Cby1 (CBY1 Products)
- Synonyms
- chibby Protein, cby Protein, arb1 Protein, pgea1 Protein, pigea14 Protein, pigea-14 Protein, hs508i15a Protein, C22orf2 Protein, CBY Protein, HS508I15A Protein, PGEA1 Protein, PIGEA-14 Protein, PIGEA14 Protein, 1110014P06Rik Protein, PGEA14 Protein, Pgea1 Protein, chibby homolog 1 S homeolog Protein, chibby homolog 1 Protein, chibby family member 1, beta catenin antagonist Protein, cby1.S Protein, cby1 Protein, CBY1 Protein, Cby1 Protein
- Background
- Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 14.3 kDa
- NCBI Accession
- NP_056188
-