ACVR1C/ALK7 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- Target See all ACVR1C/ALK7 (ACVR1C) Proteins
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 4
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ACVR1C/ALK7 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Activin receptor type 1C / ACVR1C (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ACVR1C Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Abstract
- ACVR1C Products
- Synonyms
- ACVRLK7 Protein, ALK7 Protein, Alk-7 Protein, C230097P10 Protein, Alk7 Protein, habrec1 Protein, activin A receptor type 1C Protein, activin A receptor, type IC Protein, ACVR1C Protein, Acvr1c Protein
- Background
- ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008].
- Molecular Weight
- 37.3 kDa
- NCBI Accession
- NP_001104503
- Pathways
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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