ADAMTS4 Protein (Myc-DYKDDDDK Tag)
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- Target See all ADAMTS4 Proteins
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ADAMTS4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ADAMTS4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ADAMTS4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
- Alternative Name
- Adamts4 (ADAMTS4 Products)
- Synonyms
- 3830423K05 Protein, ADAM-TS4 Protein, ADAMTS-2 Protein, ADMP-1 Protein, mKIAA0688 Protein, ADAMTS-4 Protein, ADAMTS4 Protein, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 Protein, ADAM metallopeptidase with thrombospondin type 1 motif 4 Protein, ADAM metallopeptidase with thrombospondin type 1 motif, 4 Protein, Adamts4 Protein, ADAMTS4 Protein
- Background
- Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 90 kDa
- NCBI Accession
- NP_005090
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