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AKTIP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

AKTIP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714522
  • Target See all AKTIP Proteins
    AKTIP (AKT Interacting Protein (AKTIP))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This AKTIP protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human AKTIP / FTS (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product AKTIP Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    AKTIP (AKT Interacting Protein (AKTIP))
    Alternative Name
    Aktip,fts (AKTIP Products)
    Synonyms
    FT1 Protein, FTS Protein, cb798 Protein, fts Protein, zgc:77699 Protein, fts-A Protein, aktip Protein, fts-B Protein, MGC133931 Protein, AL023020 Protein, Fif Protein, Ft Protein, Ft1 Protein, Fts Protein, AKT interacting protein Protein, akt interacting protein Protein, AKT interacting protein L homeolog Protein, AKT interacting protein S homeolog Protein, thymoma viral proto-oncogene 1 interacting protein Protein, AKTIP Protein, aktip Protein, aktip.L Protein, aktip.S Protein, Aktip Protein
    Background
    The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
    Molecular Weight
    32.9 kDa
    NCBI Accession
    NP_071921
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