ALDH8A1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all ALDH8A1 Proteins
- ALDH8A1 (Aldehyde Dehydrogenase 8 Family, Member A1 (ALDH8A1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ALDH8A1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ALDH8A1 / ALDH12 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ALDH8A1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ALDH8A1 (Aldehyde Dehydrogenase 8 Family, Member A1 (ALDH8A1))
- Alternative Name
- Aldh8a1,aldh12 (ALDH8A1 Products)
- Synonyms
- zgc:92068 Protein, wu:fi34g05 Protein, ALDH8A1 Protein, ALDH12 Protein, DJ352A20.2 Protein, Raldh4 Protein, aldehyde dehydrogenase 8 family member A1 Protein, aldehyde dehydrogenase 8 family, member A1 Protein, ALDH8A1 Protein, aldh8a1 Protein, Aldh8a1 Protein
- Background
- This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.
- Molecular Weight
- 53.2 kDa
- NCBI Accession
- NP_072090
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