A1CF Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all A1CF Proteins
- A1CF (APOBEC1 Complementation Factor (A1CF))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This A1CF protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human APOBEC1 complementation factor (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product A1CF Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- A1CF (APOBEC1 Complementation Factor (A1CF))
- Alternative Name
- Apobec1 Complementation Factor (A1CF Products)
- Synonyms
- ACF Protein, ACF64 Protein, ACF65 Protein, APOBEC1CF Protein, ASP Protein, 1810073H04Rik Protein, Acf Protein, A1cft Protein, Apobec-1 Protein, acf Protein, acf64 Protein, acf65 Protein, apobec1cf Protein, asp Protein, A1CF Protein, APOBEC1 complementation factor Protein, apobec1 complementation factor Protein, APOBEC1 complementation factor L homeolog Protein, A1CF Protein, A1cf Protein, a1cf Protein, a1cf.L Protein
- Background
- Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
- Molecular Weight
- 64.8 kDa
- NCBI Accession
- NP_620311
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