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LRP8 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

LRP8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714816
  • Target See all LRP8 Proteins
    LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    • 2
    • 2
    Human
    Source
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LRP8 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human APOER2 / LRP8 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product LRP8 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
    Alternative Name
    Apoer2,lrp8 (LRP8 Products)
    Synonyms
    LRP8 Protein, APOER2 Protein, HSZ75190 Protein, LRP-8 Protein, MCI1 Protein, 4932703M08Rik Protein, AA921429 Protein, AI848122 Protein, ApoER2 Protein, Lr8b Protein, LR8B Protein, LDL receptor related protein 8 Protein, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Protein, LRP8 Protein, Lrp8 Protein
    Background
    This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
    Molecular Weight
    74.4 kDa
    NCBI Accession
    NP_059992
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