APPL1 Protein (Myc-DYKDDDDK Tag)
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- Target See all APPL1 Proteins
- APPL1 (Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This APPL1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human APPL1 / DIP13A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product APPL1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- APPL1 (Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
- Alternative Name
- Appl1,dip13a (APPL1 Products)
- Synonyms
- APPL Protein, DIP13alpha Protein, 2900057D21Rik Protein, 7330406P05Rik Protein, AI585782 Protein, AW209077 Protein, BB022931 Protein, C88264 Protein, DIP13 Protein, RGD1309388 Protein, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Protein, adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 Protein, APPL1 Protein, Appl1 Protein
- Background
- The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
- Molecular Weight
- 79.5 kDa
- NCBI Accession
- NP_036228
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