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ATP2B2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ATP2B2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715044
  • Target See all ATP2B2 Proteins
    ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 6
    • 4
    Human
    Source
    • 6
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This ATP2B2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ATP2B2 / PMCA2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ATP2B2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
    Alternative Name
    Atp2b2,pmca2 (ATP2B2 Products)
    Synonyms
    PMCA2 Protein, PMCA2a Protein, PMCA2i Protein, ATP2B4 Protein, ATP2B2 Protein, PMCA Protein, D6Abb2e Protein, Tmy Protein, dfw Protein, jog Protein, wms Protein, wri Protein, ATPase plasma membrane Ca2+ transporting 2 Protein, ATPase, Ca++ transporting, plasma membrane 2 Protein, ATP2B2 Protein, Atp2b2 Protein, atp2b2 Protein
    Background
    The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Molecular Weight
    136.7 kDa
    NCBI Accession
    NP_001001331
    Pathways
    Sensory Perception of Sound, Regulation of Cell Size, Ribonucleoside Biosynthetic Process
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