Deoxyguanosine Kinase Protein (DGUOK) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all Deoxyguanosine Kinase (DGUOK) Proteins
- Deoxyguanosine Kinase (DGUOK)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Deoxyguanosine Kinase protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Deoxyguanosine kinase (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DGUOK Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Deoxyguanosine Kinase (DGUOK)
- Alternative Name
- Deoxyguanosine Kinase (DGUOK Products)
- Synonyms
- DGUOK Protein, zgc:86625 Protein, dgk Protein, DDBDRAFT_0218264 Protein, DDBDRAFT_0233982 Protein, DDB_0218264 Protein, DDB_0233982 Protein, MTDPS3 Protein, dGK Protein, dGK1 Protein, dGK2 Protein, dGK3 Protein, deoxyguanosine kinase Protein, deoxyguanosine kinase L homeolog Protein, DGUOK Protein, dguok Protein, dguok.L Protein, dgk Protein, Ccan_04750 Protein, Dguok Protein
- Background
- In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
- Molecular Weight
- 27.9 kDa
- NCBI Accession
- NP_550438
- Pathways
- Ribonucleoside Biosynthetic Process
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