ELAC2 Protein (Myc-DYKDDDDK Tag)
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- Target See all ELAC2 Proteins
- ELAC2 (ElaC Homolog 2 (ELAC2))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ELAC2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ELAC2 / HPC2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ELAC2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ELAC2 (ElaC Homolog 2 (ELAC2))
- Alternative Name
- Elac2,hpc2 (ELAC2 Products)
- Synonyms
- 1110017O07Rik Protein, D11Wsu80e Protein, Hpc2 Protein, ELC2 Protein, HPC2 Protein, elaC ribonuclease Z 2 Protein, ELAC2 Protein, Elac2 Protein
- Background
- The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3&apos trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 92 kDa
- NCBI Accession
- NP_060597
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