MVB12B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all MVB12B Proteins
- MVB12B (Multivesicular Body Subunit 12B (MVB12B))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MVB12B protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FAM125B (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MVB12B Protein
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Multivesicular Body Subunit 12B (MVB12B) (AA 1-221) protein (GST tag)
MVB12B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Multivesicular Body Subunit 12B (MVB12B) (AA 1-319) protein (Strep Tag)Crystallography grade MVB12B Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Multivesicular Body Subunit 12B (MVB12B) (AA 1-317) protein (Strep Tag)Crystallography grade MVB12B Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MVB12B (Multivesicular Body Subunit 12B (MVB12B))
- Alternative Name
- Fam125b (MVB12B Products)
- Synonyms
- C9orf28 Protein, FAM125B Protein, 2610200O14Rik Protein, 2610528K11Rik Protein, AI414895 Protein, Fam125b Protein, RGD1309709 Protein, fam125b Protein, mvb12b Protein, fam125ba Protein, zgc:152929 Protein, multivesicular body subunit 12B Protein, multivesicular body subunit 12B S homeolog Protein, multivesicular body subunit 12Ba Protein, MVB12B Protein, Mvb12b Protein, mvb12b.S Protein, mvb12ba Protein
- Background
- The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 24.3 kDa
- NCBI Accession
- NP_001011703
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