FERMT3 Protein (Myc-DYKDDDDK Tag)
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- Target See all FERMT3 Proteins
- FERMT3 (Fermitin Family Member 3 (FERMT3))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FERMT3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FERMT3 (transcript variant URP2SF) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FERMT3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FERMT3 (Fermitin Family Member 3 (FERMT3))
- Alternative Name
- Fermt3 (FERMT3 Products)
- Synonyms
- C79673 Protein, Kindlin3 Protein, RGD1310168 Protein, MGC69069 Protein, MGC88900 Protein, KIND3 Protein, MIG-2 Protein, MIG2B Protein, UNC112C Protein, URP2 Protein, URP2SF Protein, zgc:64101 Protein, fermitin family member 3 Protein, fermitin family member 3 L homeolog Protein, fermitin family member 3b Protein, Fermt3 Protein, fermt3.L Protein, fermt3 Protein, FERMT3 Protein, fermt3b Protein
- Background
- Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molecular Weight
- 75.2 kDa
- NCBI Accession
- NP_113659
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