FOXP3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all FOXP3 Proteins
- FOXP3 (Forkhead Box P3 (FOXP3))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FOXP3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FOXP3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FOXP3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Functional characterization of Foxp3-specific spontaneous immune responses." in: Leukemia, Vol. 27, Issue 12, pp. 2332-40, (2013) (PubMed).
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Functional characterization of Foxp3-specific spontaneous immune responses." in: Leukemia, Vol. 27, Issue 12, pp. 2332-40, (2013) (PubMed).
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- Target
- FOXP3 (Forkhead Box P3 (FOXP3))
- Alternative Name
- Foxp3 (FOXP3 Products)
- Synonyms
- foxp3 Protein, FOXP3 Protein, AIID Protein, DIETER Protein, IPEX Protein, PIDX Protein, XPID Protein, JM2 Protein, scurfin Protein, sf Protein, RGD1562112 Protein, forkhead box P3 Protein, forkhead box P3a Protein, forkhead box P3 L homeolog Protein, FOXP3 Protein, foxp3a Protein, foxp3 Protein, foxp3.L Protein, Foxp3 Protein
- Background
- The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
- Molecular Weight
- 47.1 kDa
- NCBI Accession
- NP_054728
- Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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