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GUCY2D Protein (Myc-DYKDDDDK Tag)

GUCY2D Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2722376
  • Target See all GUCY2D Proteins
    GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GUCY2D protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human GUCY2D / RETGC1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GUCY2D Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
    Alternative Name
    Gucy2d,retgc1 (GUCY2D Products)
    Synonyms
    GUCY2D Protein, CORD5 Protein, CORD6 Protein, CYGD Protein, GUC1A4 Protein, GUC2D Protein, LCA Protein, LCA1 Protein, RCD2 Protein, RETGC-1 Protein, ROS-GC1 Protein, ROSGC Protein, retGC Protein, guanylate cyclase 2D, retinal Protein, guanylate cyclase 2d Protein, GUCY2D Protein, Gucy2d Protein
    Background
    This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
    Molecular Weight
    119.9 kDa
    NCBI Accession
    NP_000171
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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