HEY2 Protein (Myc-DYKDDDDK Tag)
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- Target See all HEY2 Proteins
- HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HEY2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human HEY2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HEY2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))
- Alternative Name
- Hey2 (HEY2 Products)
- Synonyms
- CHF1 Protein, GRIDLOCK Protein, GRL Protein, HERP1 Protein, HESR2 Protein, HRT2 Protein, bHLHb32 Protein, Herp1 Protein, Hrt2 Protein, hesr2 Protein, grl Protein, zgc:136746 Protein, hes related family bHLH transcription factor with YRPW motif 2 Protein, hairy/enhancer-of-split related with YRPW motif 2 Protein, hes-related family bHLH transcription factor with YRPW motif 2 Protein, HEY2 Protein, Hey2 Protein, hey2 Protein
- Background
- This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
- Molecular Weight
- 35.6 kDa
- NCBI Accession
- NP_036391
- Pathways
- Regulation of Muscle Cell Differentiation
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