HSPB8 Protein (Myc-DYKDDDDK Tag)
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- Target See all HSPB8 Proteins
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HSPB8 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human HSPB8 / HSP22 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HSPB8 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
- Alternative Name
- Hspb8,hsp22 (HSPB8 Products)
- Synonyms
- CMT2L Protein, DHMN2 Protein, E2IG1 Protein, H11 Protein, HMN2 Protein, HMN2A Protein, HSP22 Protein, MGC64408 Protein, hsc70 Protein, wu:fb01g06 Protein, wu:fi48b06 Protein, fc09c11 Protein, wu:fc04b04 Protein, wu:fc09c11 Protein, zgc:64202 Protein, AU018630 Protein, AW413033 Protein, Cryac Protein, D5Ucla4 Protein, H11K Protein, HSP20-like Protein, Hsp22 Protein, heat shock protein family B (small) member 8 Protein, heat shock protein family B (small) member 8 L homeolog Protein, heat shock protein 8 Protein, heat shock protein b8 Protein, HSPB8 Protein, hspb8.L Protein, hspa8 Protein, hspb8 Protein, Hspb8 Protein
- Background
- The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
- Molecular Weight
- 21.4 kDa
- NCBI Accession
- NP_055180
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