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HSPB8 Protein (His tag)

HSPB8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318564
  • Target See all HSPB8 Proteins
    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
    Protein Type
    Recombinant
    Origin
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 4
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HSPB8 protein is labelled with His tag.
    Purpose
    Recombinant Human HSPB8 Protein (His Tag)
    Sequence
    Met 1-Thr196
    Characteristics
    Recombinant Human Heat shock protein beta-8 is produced by our E.coli expression system and the target gene encoding Met1-Thr196 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product HSPB8 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
    Alternative Name
    HSPB8 (HSPB8 Products)
    Synonyms
    CMT2L Protein, DHMN2 Protein, E2IG1 Protein, H11 Protein, HMN2 Protein, HMN2A Protein, HSP22 Protein, MGC64408 Protein, hsc70 Protein, wu:fb01g06 Protein, wu:fi48b06 Protein, fc09c11 Protein, wu:fc04b04 Protein, wu:fc09c11 Protein, zgc:64202 Protein, AU018630 Protein, AW413033 Protein, Cryac Protein, D5Ucla4 Protein, H11K Protein, HSP20-like Protein, Hsp22 Protein, heat shock protein family B (small) member 8 Protein, heat shock protein family B (small) member 8 L homeolog Protein, heat shock protein 8 Protein, heat shock protein b8 Protein, HSPB8 Protein, hspb8.L Protein, hspa8 Protein, hspb8 Protein, Hspb8 Protein
    Background

    Background: Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

    Synonym: Heat shock protein beta-8,HspB8,Alpha-crystallin C chain,E2-induced gene 1 protein,Protein kinase H11,Small stress protein-like protein HSP22,HSPB8,CRYAC,E2IG1,HSP22

    Molecular Weight
    22.7 kDa
    UniProt
    Q9UJY1
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