LZTS1 Protein (His tag)
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- Target See all LZTS1 Proteins
- LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LZTS1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human LZTS1 (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LZTS1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris,8M Urea, pH 8.0.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
- Alternative Name
- Lzts1 (LZTS1 Products)
- Synonyms
- F37 Protein, FEZ1 Protein, Psdzip70 Protein, LZTS1 Protein, f37 Protein, fez1 Protein, leucine zipper tumor suppressor 1 Protein, leucine zipper, putative tumor suppressor 1 Protein, LZTS1 Protein, Lzts1 Protein, lzts1 Protein
- Background
- This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
- Molecular Weight
- 66.4 kDa
- NCBI Accession
- NP_066300
- Pathways
- Synaptic Membrane
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