MGEA5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all MGEA5 Proteins
- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MGEA5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MGEA5 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MGEA5 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Thiamet-G-mediated inhibition of O-GlcNAcase sensitizes human leukemia cells to microtubule-stabilizing agent paclitaxel." in: Biochemical and biophysical research communications, Vol. 453, Issue 3, pp. 392-7, (2014) (PubMed).
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Thiamet-G-mediated inhibition of O-GlcNAcase sensitizes human leukemia cells to microtubule-stabilizing agent paclitaxel." in: Biochemical and biophysical research communications, Vol. 453, Issue 3, pp. 392-7, (2014) (PubMed).
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- Target
- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
- Alternative Name
- Mgea5 (MGEA5 Products)
- Synonyms
- MEA5 Protein, NCOAT Protein, OGA Protein, 2810009A20Rik Protein, 4833427O07Rik Protein, 5830447M11Rik Protein, AA408215 Protein, Hy5 Protein, Ncoat Protein, mKIAA0679 Protein, O-GLCNACASE Protein, cytochrome c oxidase subunit VIc Protein, meningioma expressed antigen 5 (hyaluronidase) Protein, COX6C Protein, MGEA5 Protein, Mgea5 Protein
- Background
- The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008].
- Molecular Weight
- 102.7 kDa
- NCBI Accession
- NP_036347
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
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