HMGCS2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725961

Product Details

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HMGCS2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human mHMG-CoA synthase / HMGCS2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Alternative Name: Mhmg-Coa Synthase,hmgcs2 (HMGCS2 Products)

Synonyms: 1300002P16 Protein, mHS Protein, DDBDRAFT_0219349 Protein, DDBDRAFT_0219924 Protein, DDB_0219349 Protein, DDB_0219924 Protein, Hmgcs1 Protein, Mt3h3mg Protein, hmgCoA Protein, 3-hydroxy-3-methylglutaryl-CoA synthase 2 Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 Protein, hydroxymethylglutaryl-CoA synthase Protein, hydroxymethylglutaryl-coa synthase Protein, 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 Protein, HMGCS2 Protein, Hmgcs2 Protein, mvaS Protein, CNC05080 Protein, HMCS1 Protein, hgsA Protein, MFER_RS00425 Protein, LOC100285783 Protein, ECU10_0510 Protein, Eint_100450 Protein

Background: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

Molecular Weight: 52.3 kDa

NCBI Accession: NP_005509

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha