CCL20 Protein (Transcript Variant 1)
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- Target See all CCL20 Proteins
- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human MIP3 alpha / CCL20 (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.
- Top Product
- Discover our top product CCL20 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
- Alternative Name
- Mip3 Alpha,ccl20 (CCL20 Products)
- Synonyms
- MIP-3ALPHA Protein, CCL20 Protein, si:dkey-150o13.1 Protein, CKb4 Protein, LARC Protein, MIP-3-alpha Protein, MIP-3a Protein, MIP3A Protein, SCYA20 Protein, ST38 Protein, MIP-3A Protein, MIP-3[a] Protein, Scya20 Protein, exodus-1 Protein, C-C motif chemokine ligand 20 Protein, chemokine (C-C motif) ligand 20b Protein, chemokine (C-C motif) ligand 20 Protein, CCL20 Protein, ccl20b Protein, Ccl20 Protein
- Background
- This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 8 kDa
- NCBI Accession
- NP_004582
- Pathways
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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