NECAB3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all NECAB3 Proteins
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NECAB3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NECAB3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NECAB3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
- Alternative Name
- Necab3 (NECAB3 Products)
- Synonyms
- Apba2bp Protein, APBA2BP Protein, NECAB3 Protein, EFCBP3 Protein, NIP1 Protein, STIP3 Protein, SYTIP2 Protein, XB51 Protein, dJ63M2.4 Protein, dJ63M2.5 Protein, 2900010M17Rik Protein, AI853434 Protein, Nip1 Protein, N-terminal EF-hand calcium binding protein 3 Protein, Necab3 Protein, NECAB3 Protein
- Background
- The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 40.6 kDa
- NCBI Accession
- NP_112508
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