NTAN1 Protein (Myc-DYKDDDDK Tag)
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- Target See all NTAN1 Proteins
- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NTAN1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NTAN1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NTAN1 Protein
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N-terminal Asparagine Amidase (NTAN1) (AA 1-310) protein (GST tag)
NTAN1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
N-terminal Asparagine Amidase (NTAN1) (AA 2-310) protein (His tag)Crystallography grade NTAN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
N-terminal Asparagine Amidase (NTAN1) (AA 2-310) protein (His tag)Crystallography grade NTAN1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
- Alternative Name
- Ntan1 (NTAN1 Products)
- Synonyms
- PNAA Protein, PNAD Protein, N-terminal Asn amidase Protein, N-terminal asparagine amidase Protein, Ntan1 Protein, NTAN1 Protein
- Background
- The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
- Molecular Weight
- 34.5 kDa
- NCBI Accession
- NP_775745
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