Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

NUMB Protein (DYKDDDDK Tag)

NUMB Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2727805
  • Target See all NUMB Proteins
    NUMB (Numb Homolog (NUMB))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    Insect cells (Sf9)
    Purification tag / Conjugate
    This NUMB protein is labelled with DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human NUMB (C-term flag tag) protein expressed in Sf9 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NUMB Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 5 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    NUMB (Numb Homolog (NUMB))
    Alternative Name
    Numb (NUMB Products)
    Synonyms
    C14orf41 Protein, S171 Protein, c14_5527 Protein, Nb Protein, NUMB, endocytic adaptor protein Protein, numb homolog (Drosophila) Protein, NUMB Protein, Numb Protein, numb Protein
    Background
    Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    66 kDa
    NCBI Accession
    NP_001005744
    Pathways
    Cell-Cell Junction Organization
You are here:
Support