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Nyctalopin Protein (NYX) (Myc-DYKDDDDK Tag)

NYX Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2727840
  • Target See all Nyctalopin (NYX) Proteins
    Nyctalopin (NYX)
    Protein Type
    Recombinant
    Origin
    • 1
    • 1
    Human
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Nyctalopin protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Nyctalopin protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NYX Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Nyctalopin (NYX)
    Alternative Name
    Nyctalopin (NYX Products)
    Synonyms
    MGC84276 Protein, CLRP Protein, CSNB1 Protein, CSNB1A Protein, CSNB4 Protein, NBM1 Protein, CLNP Protein, nob Protein, RGD1561300 Protein, nyctalopin Protein, nyctalopin L homeolog Protein, uncharacterized LOC491837 Protein, NYX Protein, nyx.L Protein, LOC491837 Protein, nyx Protein, Nyx Protein
    Background
    The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
    Molecular Weight
    49.5 kDa
    NCBI Accession
    NP_072089
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